The browser allows interactive exploration of data generated by the Cores, along with associated external data. The intention is to provide researchers with the ability to identify relationships between data generated by the various Cores, in order to gain insights that can drive their own research. To begin interactive exploration, one enters the name of any gene in the Integrated Data Browser's "Gene Search" search box to retrieve the data related to that gene. Interactive exploration will develop over time to include additional data sources and searches.
For any gene or protein of interest, the search provides available
Each of these functionalities is provided in one or more separate web page panels, or "portlets":
Gene Search
Launches the search for data associated with a given gene.
Gene Summary
Displays, and links out to, associated gene annotations from external and consortium Core data sources.
Gene Expression Studies
Gene expression profiles obtained from consortium
3' expression arrays
arrays are displayed graphically and in a table. The user can select any subset of available experimental conditions for display, using a selection box. Expression values are generated using the
3' array processing pipeline.
Genomic Annotations and Features
Provides gene structure information, binding regions identified by
ChIP-on-chip studies,
and
predicted binding sites
in the vicinity of the gene.
Each feature is listed in terms of mouse genome coordinates.
For ChIP-on-chip features, the protein used for the IP is given, as well as pertinent experimental conditions,
such as time after cell stimulation.
Predicted transcription factor binding sites in the region are obtained from motif scanning.
Each potential site is annotated with a specific motif model (Position Weight Matrix) identifier and score indicating the quality of the match.
Details of how to use each portlet can be accessed by clicking on the "?" button.